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Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin

Analysis of the Polyp Prevention Trial showed an association between isorhamnetin-rich diet and a reduced risk of advanced adenoma recurrence; however, the mechanism of isorhamnetin’s chemoprotective effects remains unclear. Here we demonstrate that isorhamnetin prevents colorectal tumorigenesis of...

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Detalhes bibliográficos
Main Authors: Saud, Shakir M., Young, Matthew R., Jones-Hall, Yava L., Ileva, Lilia, Evbuomwan, Moses O., Wise, Jennifer, Colburn, Nancy H., Kim, Young S., Bobe, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870026/
https://ncbi.nlm.nih.gov/pubmed/23824743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0525
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