Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression

Sporadic and non-hereditary mutations account for the majority of colorectal cancers (CRC). After the loss of adenomatous polyposis coli (APC) function and activation of the β-catenin/LEF signaling pathway, activating mutations in Kras are major drivers of sporadic CRC. Preventing the outgrowth of c...

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Gepubliceerd in:Carcinogenesis
Hoofdauteurs: Saud, Shakir M., Li, Weidong, Morris, Nicole L., Matter, Matthias S., Colburn, Nancy H., Kim, Young S., Young, Matthew R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247523/
https://ncbi.nlm.nih.gov/pubmed/25280562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgu209
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