Comparative transcriptomic analysis reveals the oncogenic fusion protein PAX3-FOXO1 globally alters mRNA and miRNA to enhance myoblast invasion

Rhabdomyosarcoma, one of the most common childhood sarcomas, is comprised of two main subtypes, embryonal and alveolar (ARMS). ARMS, the more aggressive subtype, is primarily characterized by the t(2;13)(p35;p14) chromosomal translocation, which fuses two transcription factors, PAX3 and FOXO1 to gen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogenesis
Prif Awduron: Loupe, J M, Miller, P J, Bonner, B P, Maggi, E C, Vijayaraghavan, J, Crabtree, J S, Taylor, C M, Zabaleta, J, Hollenbach, A D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Short Communication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972903/
https://ncbi.nlm.nih.gov/pubmed/27454080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.53
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