Comparative transcriptomic analysis reveals the oncogenic fusion protein PAX3-FOXO1 globally alters mRNA and miRNA to enhance myoblast invasion

Rhabdomyosarcoma, one of the most common childhood sarcomas, is comprised of two main subtypes, embryonal and alveolar (ARMS). ARMS, the more aggressive subtype, is primarily characterized by the t(2;13)(p35;p14) chromosomal translocation, which fuses two transcription factors, PAX3 and FOXO1 to gen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncogenesis
Egile Nagusiak: Loupe, J M, Miller, P J, Bonner, B P, Maggi, E C, Vijayaraghavan, J, Crabtree, J S, Taylor, C M, Zabaleta, J, Hollenbach, A D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Short Communication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972903/
https://ncbi.nlm.nih.gov/pubmed/27454080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2016.53
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