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SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages
We previously observed that SNAPIN, which is an adaptor protein in the SNARE core complex, was highly expressed in rheumatoid arthritis synovial tissue macrophages, but its role in macrophages and autoimmunity is unknown. To identify SNAPIN's role in these cells, we employed siRNA to silence th...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Autophagy |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5324844/ https://ncbi.nlm.nih.gov/pubmed/27929705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1261238 |
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