Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene

Cellular cholesterol metabolism is subject to tight regulation to maintain adequate levels of this central lipid molecule. Herein, the sterol-responsive Liver X Receptors (LXRs) play an important role owing to their ability to reduce cellular cholesterol load. In this context, identifying the full s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cook, Emma C. L., Nelson, Jessica K., Sorrentino, Vincenzo, Koenis, Duco, Moeton, Martina, Scheij, Saskia, Ottenhoff, Roelof, Bleijlevens, Boris, Loregger, Anke, Zelcer, Noam
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5322959/
https://ncbi.nlm.nih.gov/pubmed/28231341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172721
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