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Resurrecting KIR2DP1 a Key Intermediate in the Evolution of Human Inhibitory NK cell Receptors that Recognize HLA-C
KIR2DP1 is an inactive member of the human lineage III KIR family, which includes all HLA-C specific receptors. The lethal, and only, defect in KIR2DP1 is a nucleotide deletion in codon 88. Fixed in modern humans, the deletion is also in archaic human genomes. KIR2DP1 is polymorphic, with dimorphism...
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| Yayımlandı: | J Immunol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5321844/ https://ncbi.nlm.nih.gov/pubmed/28122963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601835 |
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