Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation

Acute Myeloid Leukemia (AML) is a highly heterogeneous and poor prognosis disease with few available therapeutic options. Novel advances are urgently needed, however effective models to test experimental therapeutics have been lacking. Recently, NOD/SCID/IL2rγnull (NSG) mice were shown to engraft pr...

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Detalhes bibliográficos
Publicado no:J Leuk (Los Angel)
Main Authors: Barth, Brian M, Keasey, Nichole R, Wang, Xujung, Shanmugavelandy, Sriram S, Rampal, Raajit, Hricik, Todd, Cabot, Myles C, Kester, Mark, Wang, Hong-Gang, Shultz, Leonard D, Tallman, Martin S, Levine, Ross L, Loughran, Thomas P, Claxton, David F
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321614/
https://ncbi.nlm.nih.gov/pubmed/28239612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2329-6917.1000146
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