Improved Engraftment of Human Spleen Cells in NOD/LtSz-scid/scid Mice as Compared with C.B-17-scid/scid Mice

T and B lymphocyte-deficient mice homozygous for the severe combined immunodeficiency (SCID) mutation can be immunologically engrafted with human lymphocytes. However, low levels of human peripheral blood mononuclear cell engraftment are commonly observed, impeding full use of this model We now demo...

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Main Authors: Greiner, Dale L., Shultz, Leonard D., Yates, Jon, Appel, Michael C., Perdrizet, George, Hesselton, RuthAnn M., Schweitzer, Isabelle, Beamer, Wes G., Shultz, Kathryn L., Pelsue, Stephen C., Leif, Jean H., Rajan, Thiruchandurai V.
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869266/
https://ncbi.nlm.nih.gov/pubmed/7717456
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