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Busulfan produces efficient human cell engraftment in NOD/LtSz-scid IL2Rγ null mice
Xenografting immunodeficient mice after low-dose irradiation has been employed as a surrogate human hematopoietic stem cell (HSC) assay; however, irradiation requires strict and meticulous animal support and can produce significant mortality rates, limiting the usefulness of this model. In this work...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696310/ https://ncbi.nlm.nih.gov/pubmed/18927475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0583 |
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