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Dynamics of ceramide generation and metabolism in response to fenretinide--diversity within and among leukemia
Fenretinide, N-(4-hydroxyphenyl)retinamide, (4-HPR), a synthetic retinoid, owes its cancer-toxic effects in part to the generation of ceramide, a potent tumor-suppressing sphingolipid. As such, 4-HPR has garnered considerable interest as a chemotherapeutic. Cancer cells, however, via various metabol...
Sparad:
| I publikationen: | Leuk Res |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573880/ https://ncbi.nlm.nih.gov/pubmed/26220867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2015.06.009 |
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