A novel chemical biology approach for mapping of polymyxin-lipopeptide antibody binding epitopes

Polymyxin B and E (i.e. colistin) are a family of naturally occurring lipopeptide antibiotics that are our last-line of defense against MDR Gram-negative pathogens. Unfortunately, nephrotoxicity is a dose-limiting factor for polymyxins which limits their clinical utility. Our recent studies demonstr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Infect Dis
Main Authors: Velkov, Tony, Yun, Bo, Schneider, Elena K., Azad, Mohammad A. K., Dolezal, Olan, Morris, Faye C., Nation, Roger L., Wang, Jiping, Chen, Ke, Yu, Heidi H., Chen, Lv, Thompson, Philip E., Roberts, Kade D., Li, Jian
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321607/
https://ncbi.nlm.nih.gov/pubmed/27627202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00031
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