A novel chemical biology approach for mapping of polymyxin-lipopeptide antibody binding epitopes

Polymyxin B and E (i.e. colistin) are a family of naturally occurring lipopeptide antibiotics that are our last-line of defense against MDR Gram-negative pathogens. Unfortunately, nephrotoxicity is a dose-limiting factor for polymyxins which limits their clinical utility. Our recent studies demonstr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:ACS Infect Dis
Päätekijät: Velkov, Tony, Yun, Bo, Schneider, Elena K., Azad, Mohammad A. K., Dolezal, Olan, Morris, Faye C., Nation, Roger L., Wang, Jiping, Chen, Ke, Yu, Heidi H., Chen, Lv, Thompson, Philip E., Roberts, Kade D., Li, Jian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321607/
https://ncbi.nlm.nih.gov/pubmed/27627202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.6b00031
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