Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors

Tumor-associated macrophages (TAM) and myofibroblasts are key drivers in cancer that are associated with drug resistance in many cancers, including pancreatic ductal adenocarcinoma (PDAC). However, our understanding of the molecular mechanisms by which TAM and fibroblasts contribute to chemoresistan...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Ireland, Lucy, Santos, Almudena, Ahmed, Muhammad S., Rainer, Carolyn, Nielsen, Sebastian R., Quaranta, Valeria, Weyer-Czernilofsky, Ulrike, Engle, Danielle D., Perez-Mancera, Pedro A., Coupland, Sarah E., Taktak, Azzam, Bogenrieder, Thomas, Tuveson, David A., Campbell, Fiona, Schmid, Michael C., Mielgo, Ainhoa
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5321488/
https://ncbi.nlm.nih.gov/pubmed/27742686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1201
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