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Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer
Effector T cells and fibroblasts are major components in the tumor microenvironment. The means through which these cellular interactions affect chemoresistance is unclear. Here, we show that fibroblasts diminish nuclear accumulation of platinum in ovarian cancer cells, resulting in resistance to pla...
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| Publicat a: | Cell |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874853/ https://ncbi.nlm.nih.gov/pubmed/27133165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.009 |
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