Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer

Effector T cells and fibroblasts are major components in the tumor microenvironment. The means through which these cellular interactions affect chemoresistance is unclear. Here, we show that fibroblasts diminish nuclear accumulation of platinum in ovarian cancer cells, resulting in resistance to pla...

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發表在:Cell
Main Authors: Wang, Weimin, Kryczek, Ilona, Dostál, Lubomír, Lin, Heng, Tan, Lijun, Zhao, Lili, Lu, Fujia, Wei, Shuang, Maj, Tomasz, Peng, Dongjun, He, Gong, Vatan, Linda, Szeliga, Wojciech, Kuick, Rork, Kotarski, Jan, Tarkowski, Rafał, Dou, Yali, Rattan, Ramandeep, Munkarah, Adnan, Liu, J. Rebecca, Zou, Weiping
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874853/
https://ncbi.nlm.nih.gov/pubmed/27133165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.009
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