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Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen
Targeted cancer therapeutics aim to exploit tumor-specific, genetic vulnerabilities specifically affecting neoplastic cells without similarly affecting normal cells. Here we performed sequencing-based screening of an shRNA library on a panel of cancer cells of different origins as well as normal cel...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5320502/ https://ncbi.nlm.nih.gov/pubmed/28223711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43023 |
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