Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis

Activation of the hypoxia-inducible factor (HIF)-pathway in hepatocellular carcinoma (HCC) induces therapy resistant tumours, characterized by increased liver progenitor cell (LPCs) characteristics and poor prognosis. We previously reported corresponding results in mice with HCC in which hypoxia was...

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書目詳細資料
發表在:EXCLI J
Main Authors: Bogaerts, Eliene, Paridaens, Annelies, Verhelst, Xavier, Carmeliet, Peter, Geerts, Anja, Van Vlierberghe, Hans, Devisscher, Lindsey
格式: Artigo
語言:Inglês
出版: Leibniz Research Centre for Working Environment and Human Factors 2016
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318796/
https://ncbi.nlm.nih.gov/pubmed/28337100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2016-607
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