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The I(Cl,swell) inhibitor DCPIB blocks Kir channels that possess weak affinity for PIP(2)

Inwardly rectifying K(+) (Kir) channels are important contributors to the resting membrane potential and regulate cellular excitability. The activity of Kir channels depends critically on the phospholipid PIP(2). Several modulators of the activity of Kir channels alter the apparent affinity of the c...

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Dades bibliogràfiques
Publicat a:Pflugers Arch
Autors principals: Deng, Wu, Mahajan, Rahul, Baumgarten, Clive M., Logothetis, Diomedes E.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5317042/
https://ncbi.nlm.nih.gov/pubmed/26837888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1794-9
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