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Optimizing T-cell receptor gene therapy for hematologic malignancies

Recent advances in genetic engineering have enabled the delivery of clinical trials using patient T cells redirected to recognize tumor-associated antigens. The most dramatic results have been seen with T cells engineered to express a chimeric antigen receptor (CAR) specific for CD19, a differentiat...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Morris, Emma C., Stauss, Hans J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316910/
https://ncbi.nlm.nih.gov/pubmed/27207802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-11-629071
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