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Molecular immunology lessons from therapeutic T-cell receptor gene transfer

The T-cell receptor (TCR) is critical for T-cell lineage selection, antigen specificity, effector function and survival. Recently, TCR gene transfer has been developed as a reliable method to generate ex vivo large numbers of T cells of a given antigen-specificity and functional avidity. Such approa...

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Detalhes bibliográficos
Main Authors: Thomas, Sharyn, Stauss, Hans J, Morris, Emma C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814459/
https://ncbi.nlm.nih.gov/pubmed/20561357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03227.x
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