miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal

Mice harboring a G12D activating Kras mutation are among the most heavily studied models in the field of pancreatic adenocarcinoma (PDAC) research. miRNAs are differentially expressed in PDAC from patients and mouse models of PDAC. To better understand the relationship that Kras activation has on mi...

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Detaylı Bibliyografya
Yayımlandı:Funct Integr Genomics
Asıl Yazarlar: Azevedo-Pouly, Ana Clara P., Sutaria, Dhruvitkumar S., Jiang, Jinmai, Elgamal, Ola A., Amari, Foued, Allard, David, Grippo, Paul J., Coppola, Vincenzo, Schmittgen, Thomas D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316511/
https://ncbi.nlm.nih.gov/pubmed/27541609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10142-016-0512-1
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