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miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal

Mice harboring a G12D activating Kras mutation are among the most heavily studied models in the field of pancreatic adenocarcinoma (PDAC) research. miRNAs are differentially expressed in PDAC from patients and mouse models of PDAC. To better understand the relationship that Kras activation has on mi...

詳細記述

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書誌詳細
出版年:Funct Integr Genomics
主要な著者: Azevedo-Pouly, Ana Clara P., Sutaria, Dhruvitkumar S., Jiang, Jinmai, Elgamal, Ola A., Amari, Foued, Allard, David, Grippo, Paul J., Coppola, Vincenzo, Schmittgen, Thomas D.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316511/
https://ncbi.nlm.nih.gov/pubmed/27541609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10142-016-0512-1
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