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Regulation of Heme Oxygenase-1 Protein Expression by miR-377 in Combination with miR-217

Heme oxygenase-1 (HO-1) enzyme plays a critical role in metabolizing the excess heme generated during hemolysis. Our previous studies suggested that during intravascular hemolysis the expression of HO-1 protein is not sufficient to reduce the oxidative burden of free heme in the vasculature. This le...

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Detalhes bibliográficos
Main Authors: Beckman, Joan D., Chen, Chunseng, Nguyen, Julia, Thayanithy, Venugopal, Subramanian, Subbaya, Steer, Clifford J., Vercellotti, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030323/
https://ncbi.nlm.nih.gov/pubmed/21106538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.148726
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