Tumor-stromal cross-talk: Direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes

Tunneling nanotubes (TnTs) represent a novel mechanism by which intercellular components such as proteins, Golgi vesicles, and mitochondria can be transferred from cell to cell in the complex tumor microenvironment. Here, we report data showing that microRNAs (miRNAs) are transferred through TnTs in...

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Veröffentlicht in:Transl Res
Hauptverfasser: Thayanithy, Venugopal, Dickson, Elizabeth L., Steer, Clifford, Subramanian, Subbaya, Lou, Emil
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242806/
https://ncbi.nlm.nih.gov/pubmed/24929208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2014.05.011
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