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Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

In this study, we demonstrated that hypoxic conditions stimulated an increase in tunneling nanotube (TNT) formation in chemoresistant ovarian cancer cells (SKOV3, C200). We found that suppressing the mTOR pathway using either everolimus or metformin led to suppression of TNT formation in vitro, veri...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Desir, Snider, Dickson, Elizabeth L., Vogel, Rachel I., Thayanithy, Venugopal, Wong, Phillip, Teoh, Deanna, Geller, Melissa A., Steer, Clifford J., Subramanian, Subbaya, Lou, Emil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190014/
https://ncbi.nlm.nih.gov/pubmed/27223082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9504
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