Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells

In this study, we demonstrated that hypoxic conditions stimulated an increase in tunneling nanotube (TNT) formation in chemoresistant ovarian cancer cells (SKOV3, C200). We found that suppressing the mTOR pathway using either everolimus or metformin led to suppression of TNT formation in vitro, veri...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Desir, Snider, Dickson, Elizabeth L., Vogel, Rachel I., Thayanithy, Venugopal, Wong, Phillip, Teoh, Deanna, Geller, Melissa A., Steer, Clifford J., Subramanian, Subbaya, Lou, Emil
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5190014/
https://ncbi.nlm.nih.gov/pubmed/27223082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9504
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