Carregant...

c9orf72 Disease-Related Foci are Each Composed of One Mutant Expanded Repeat RNA

The chromosome 9 open reading frame 72 (c9orf72) gene contains a hexanucleotide (GGGGCC) repeat expansion responsible for many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The mutant intronic RNA forms “foci” within nuclei, but the connection between transcript exp...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Chem Biol
Autors principals: Liu, Jing, Hu, Jiaxin, Ludlow, Andrew, Pham, Jackie, Shay, Jerry W., Rothstein, Jeffrey D., Corey, David R.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5316317/
https://ncbi.nlm.nih.gov/pubmed/28132891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.12.018
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!