A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinomas (PDACs) constitutively express the G-protein-coupled cholecystokinin B receptor (CCKBR). In this study, we identified DNA aptamers (APs) that bind to the CCKBR and describe their characterization and targeting efficacy. Using dual SELEX selection against “exposed” C...

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Detalhes bibliográficos
Publicado no:Nucleic Acid Ther
Main Authors: Clawson, Gary A., Abraham, Thomas, Pan, Weihua, Tang, Xiaomeng, Linton, Samuel S., McGovern, Christopher O., Loc, Welley S., Smith, Jill P., Butler, Peter J., Kester, Mark, Adair, James H., Matters, Gail L.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312616/
https://ncbi.nlm.nih.gov/pubmed/27754762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2016.0621
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