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A Speculative Role for Stromal Gastrin Signaling in Development and Dissemination of Pancreatic Ductal Adenocarcinoma

The peptide growth factor gastrin and its receptor, the G-protein coupled cholecystokinin receptor type B (CCK(B)R), play an integral role in the growth and progression of pancreatic ductal adenocarcinoma (PDAC). Gastrin immunoreactivity is found in the fetal pancreas but its expression is not detec...

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Bibliographic Details
Main Authors: Matters, Gail L, Clawson, Gary A
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208305/
https://ncbi.nlm.nih.gov/pubmed/25346875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2165-7092.S4-003
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