Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix

Desmoplasia describes the deposition of extensive extracellular matrix and defines primary pancreatic ductal adenocarcinoma (PDA). The acellular component of this stroma has been implicated in PDA pathogenesis and is being targeted therapeutically in clinical trials. By analyzing the stromal content...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Jiang, Honglin, Torphy, Robert J., Steiger, Katja, Hongo, Henry, Ritchie, Alexa J., Kriegsmann, Mark, Horst, David, Umetsu, Sarah E., Joseph, Nancy M., McGregor, Kimberly, Pishvaian, Michael J., Blais, Edik M., Lu, Brian, Li, Mingyu, Hollingsworth, Michael, Stashko, Connor, Volmar, Keith, Yeh, Jen Jen, Weaver, Valerie M., Wang, Zhen J., Tempero, Margaret A., Weichert, Wilko, Collisson, Eric A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Concise Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456216/
https://ncbi.nlm.nih.gov/pubmed/32749238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136760
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