Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix

Desmoplasia describes the deposition of extensive extracellular matrix and defines primary pancreatic ductal adenocarcinoma (PDA). The acellular component of this stroma has been implicated in PDA pathogenesis and is being targeted therapeutically in clinical trials. By analyzing the stromal content...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Jiang, Honglin, Torphy, Robert J., Steiger, Katja, Hongo, Henry, Ritchie, Alexa J., Kriegsmann, Mark, Horst, David, Umetsu, Sarah E., Joseph, Nancy M., McGregor, Kimberly, Pishvaian, Michael J., Blais, Edik M., Lu, Brian, Li, Mingyu, Hollingsworth, Michael, Stashko, Connor, Volmar, Keith, Yeh, Jen Jen, Weaver, Valerie M., Wang, Zhen J., Tempero, Margaret A., Weichert, Wilko, Collisson, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2020
Assuntos:
Concise Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456216/
https://ncbi.nlm.nih.gov/pubmed/32749238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136760
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