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De novo compartment deconvolution and weight estimation of tumor samples using DECODER

Tumors are mixtures of different compartments. While global gene expression analysis profiles the average expression of all compartments in a sample, identifying the specific contribution of each compartment remains a challenge. With the increasing recognition of the importance of non-neoplastic com...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Peng, Xianlu Laura, Moffitt, Richard A., Torphy, Robert J., Volmar, Keith E., Yeh, Jen Jen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802116/
https://ncbi.nlm.nih.gov/pubmed/31628300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12517-7
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