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Implications of non-uniqueness in phylogenetic deconvolution of bulk DNA samples of tumors
BACKGROUND: Tumors exhibit extensive intra-tumor heterogeneity, the presence of groups of cellular populations with distinct sets of somatic mutations. This heterogeneity is the result of an evolutionary process, described by a phylogenetic tree. In addition to enabling clinicians to devise patient-...
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| Veröffentlicht in: | Algorithms Mol Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719395/ https://ncbi.nlm.nih.gov/pubmed/31497065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-019-0155-6 |
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