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Phylogenetic Copy-Number Factorization of Multiple Tumor Samples

Cancer is an evolutionary process driven by somatic mutations. This process can be represented as a phylogenetic tree. Constructing such a phylogenetic tree from genome sequencing data is a challenging task due to the many types of mutations in cancer and the fact that nearly all cancer sequencing i...

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Detalles Bibliográficos
Publicado en:J Comput Biol
Autores principales: Zaccaria, Simone, El-Kebir, Mohammed, Klau, Gunnar W., Raphael, Benjamin J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067108/
https://ncbi.nlm.nih.gov/pubmed/29658782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2017.0253
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