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Accurate quantification of copy-number aberrations and whole-genome duplications in multi-sample tumor sequencing data
Copy-number aberrations (CNAs) and whole-genome duplications (WGDs) are frequent somatic mutations in cancer but their quantification from DNA sequencing of bulk tumor samples is challenging. Standard methods for CNA inference analyze tumor samples individually; however, DNA sequencing of multiple s...
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| Publicado en: | Nat Commun |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7468132/ https://ncbi.nlm.nih.gov/pubmed/32879317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17967-y |
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