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SCARLET: Single-cell tumor phylogeny inference with copy-number constrained mutation losses
A small number of somatic mutations drive the development of cancer, but all somatic mutations are markers of the evolutionary history of a tumor. Prominent methods to construct phylogenies from single-cell sequencing data use single-nucleotide variants (SNVs) as markers but fail to adequately accou...
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| Udgivet i: | Cell Syst |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451135/ https://ncbi.nlm.nih.gov/pubmed/32864481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.04.001 |
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