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FastClone is a probabilistic tool for deconvoluting tumor heterogeneity in bulk-sequencing samples

Dissecting tumor heterogeneity is a key to understanding the complex mechanisms underlying drug resistance in cancers. The rich literature of pioneering studies on tumor heterogeneity analysis spurred a recent community-wide benchmark study that compares diverse modeling algorithms. Here we present...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Xiao, Yao, Wang, Xueqing, Zhang, Hongjiu, Ulintz, Peter J., Li, Hongyang, Guan, Yuanfang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478963/
https://ncbi.nlm.nih.gov/pubmed/32901013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18169-2
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