A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinomas (PDACs) constitutively express the G-protein-coupled cholecystokinin B receptor (CCKBR). In this study, we identified DNA aptamers (APs) that bind to the CCKBR and describe their characterization and targeting efficacy. Using dual SELEX selection against “exposed” C...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acid Ther
Prif Awduron: Clawson, Gary A., Abraham, Thomas, Pan, Weihua, Tang, Xiaomeng, Linton, Samuel S., McGovern, Christopher O., Loc, Welley S., Smith, Jill P., Butler, Peter J., Kester, Mark, Adair, James H., Matters, Gail L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2017
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312616/
https://ncbi.nlm.nih.gov/pubmed/27754762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2016.0621
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