A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinomas (PDACs) constitutively express the G-protein-coupled cholecystokinin B receptor (CCKBR). In this study, we identified DNA aptamers (APs) that bind to the CCKBR and describe their characterization and targeting efficacy. Using dual SELEX selection against “exposed” C...

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Detalles Bibliográficos
Publicado en:Nucleic Acid Ther
Main Authors: Clawson, Gary A., Abraham, Thomas, Pan, Weihua, Tang, Xiaomeng, Linton, Samuel S., McGovern, Christopher O., Loc, Welley S., Smith, Jill P., Butler, Peter J., Kester, Mark, Adair, James H., Matters, Gail L.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2017
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312616/
https://ncbi.nlm.nih.gov/pubmed/27754762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2016.0621
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