USP9X destabilizes pVHL and promotes cell proliferation

Numerous mutations of the Von Hippel-Lindau (VHL) gene have been reported to cause dysfunction of VHL protein (pVHL) and lead to processes related to tumor progression. pVHL acts as an E3 ligase and degrades downstream targets, such as hypoxia-inducible transcription factor (HIF) which is essential...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Cong, Peng, Zuohan, Zhu, Minglu, Wang, Penglong, Du, Xiao, Li, Xiang, Liu, Yu, Jin, Yan, McNutt, Michael A., Yin, Yuxin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312400/
https://ncbi.nlm.nih.gov/pubmed/27517496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11139
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados