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pVHL Function Is Essential for Endothelial Extracellular Matrix Deposition

The tumor suppressor von Hippel-Lindau protein (pVHL) is critical for cellular molecular oxygen sensing, acting to target degradation of the hypoxia-inducible factor alpha transcription factor subunits under normoxic conditions. We have found that independent of its function in regulating hypoxic re...

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Détails bibliographiques
Auteurs principaux: Tang, Nan, Mack, Fiona, Haase, Volker H., Simon, M. Celeste, Johnson, Randall S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430327/
https://ncbi.nlm.nih.gov/pubmed/16537898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.7.2519-2530.2006
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