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The influence of AccD5 on AccD6 carboxyltransferase essentiality in pathogenic and non-pathogenic Mycobacterium

Malonyl-coenzyme A (CoA) is a crucial extender unit for the synthesis of mycolic and other fatty acids in mycobacteria, generated in a reaction catalyzed by acetyl-CoA carboxylase. We previously reported on the essentiality of accD6(Mtb) encoding the functional acetyl-CoA carboxylase subunit in Myco...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pawelczyk, Jakub, Viljoen, Albertus, Kremer, Laurent, Dziadek, Jaroslaw
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311964/
https://ncbi.nlm.nih.gov/pubmed/28205597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42692
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