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AccD6, a Key Carboxyltransferase Essential for Mycolic Acid Synthesis in Mycobacterium tuberculosis, Is Dispensable in a Nonpathogenic Strain

Acetyl coenzyme A carboxylase (ACC) is a key enzyme providing a substrate for mycolic acid biosynthesis. Although in vitro studies have demonstrated that the protein encoded by accD6 (Rv2247) may be a functional carboxyltransferase subunit of ACC in Mycobacterium tuberculosis, the in vivo function a...

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Detalhes bibliográficos
Main Authors: Pawelczyk, Jakub, Brzostek, Anna, Kremer, Laurent, Dziadek, Bozena, Rumijowska-Galewicz, Anna, Fiolka, Marta, Dziadek, Jaroslaw
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232849/
https://ncbi.nlm.nih.gov/pubmed/21984794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05638-11
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