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Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that can adapt to the various nutrients available during its life cycle. However, in the nutritionally stringent environment of the macrophage phagolysosome, Mtb relies mainly on cholesterol. In previous studies, we demonstrated that Mtb...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pawełczyk, Jakub, Brzostek, Anna, Minias, Alina, Płociński, Przemysław, Rumijowska-Galewicz, Anna, Strapagiel, Dominik, Zakrzewska-Czerwińska, Jolanta, Dziadek, Jarosław
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196197/
https://ncbi.nlm.nih.gov/pubmed/34117327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91812-0
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