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Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesis

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that can adapt to the various nutrients available during its life cycle. However, in the nutritionally stringent environment of the macrophage phagolysosome, Mtb relies mainly on cholesterol. In previous studies, we demonstrated that Mtb...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Pawełczyk, Jakub, Brzostek, Anna, Minias, Alina, Płociński, Przemysław, Rumijowska-Galewicz, Anna, Strapagiel, Dominik, Zakrzewska-Czerwińska, Jolanta, Dziadek, Jarosław
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8196197/
https://ncbi.nlm.nih.gov/pubmed/34117327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-91812-0
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