Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness

Toll-like receptors (TLR) provide a critical link between innate and adaptive immunity, both important players in atherosclerosis. Since evidence for the role of TLR5 is lacking, we aimed to establish this in the immune axis of atherosclerosis. We assessed the effect of the TLR5-specific ligand Flag...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Ellenbroek, Guilielmus H.J.M., van Puijvelde, Gijs H.M., Anas, Adam A., Bot, Martine, Asbach, Miriam, Schoneveld, Arjan, van Santbrink, Peter J., Foks, Amanda C., Timmers, Leo, Doevendans, Pieter A., Pasterkamp, Gerard, Hoefer, Imo E., van der Poll, Tom, Kuiper, Johan, de Jager, Saskia C.A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311952/
https://ncbi.nlm.nih.gov/pubmed/28202909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42688
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