Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis

Macroautophagy (or autophagy) is a conserved cellular process in which cytoplasmic cargo is targeted for lysosomal degradation. Autophagy is crucial for the functional integrity of different subsets of T cells in various developmental stages. Since atherosclerosis is an inflammatory disease of the v...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Amersfoort, Jacob, Douna, Hidde, Schaftenaar, Frank H., Foks, Amanda C., Kröner, Mara J., van Santbrink, Peter J., van Puijvelde, Gijs H. M., Bot, Ilze, Kuiper, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299070/
https://ncbi.nlm.nih.gov/pubmed/30619297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02937
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