Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness

Toll-like receptors (TLR) provide a critical link between innate and adaptive immunity, both important players in atherosclerosis. Since evidence for the role of TLR5 is lacking, we aimed to establish this in the immune axis of atherosclerosis. We assessed the effect of the TLR5-specific ligand Flag...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Ellenbroek, Guilielmus H.J.M., van Puijvelde, Gijs H.M., Anas, Adam A., Bot, Martine, Asbach, Miriam, Schoneveld, Arjan, van Santbrink, Peter J., Foks, Amanda C., Timmers, Leo, Doevendans, Pieter A., Pasterkamp, Gerard, Hoefer, Imo E., van der Poll, Tom, Kuiper, Johan, de Jager, Saskia C.A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311952/
https://ncbi.nlm.nih.gov/pubmed/28202909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42688
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk