Human CD4(+) T Cell Responses to an Attenuated Tetravalent Dengue Vaccine Parallel Those Induced by Natural Infection in Magnitude, HLA Restriction, and Antigen Specificity

Dengue virus (DENV) is responsible for growing numbers of infections worldwide and has proven to be a significant challenge for vaccine development. We previously demonstrated that CD8(+) T cell responses elicited by a dengue live attenuated virus (DLAV) vaccine resemble those observed after natural...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Angelo, Michael A., Grifoni, Alba, O'Rourke, Patrick H., Sidney, John, Paul, Sinu, Peters, Bjoern, de Silva, Aruna D., Phillips, Elizabeth, Mallal, Simon, Diehl, Sean A., Kirkpatrick, Beth D., Whitehead, Stephen S., Durbin, Anna P., Sette, Alessandro, Weiskopf, Daniela
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309943/
https://ncbi.nlm.nih.gov/pubmed/27974563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02147-16
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