Characterization of Magnitude and Antigen Specificity of HLA-DP, DQ, and DRB3/4/5 Restricted DENV-Specific CD4+ T Cell Responses

Background: Dengue Virus (DENV) associated disease is a major public health problem. Assessment of HLA class II restricted DENV-specific responses is relevant for immunopathology and definition of correlates of protection. While previous studies characterized responses restricted by the HLA-DRB1 loc...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Grifoni, Alba, Moore, Eugene, Voic, Hannah, Sidney, John, Phillips, Elizabeth, Jadi, Ramesh, Mallal, Simon, De Silva, Aruna D., De Silva, Aravinda M., Peters, Bjoern, Weiskopf, Daniela, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6624677/
https://ncbi.nlm.nih.gov/pubmed/31333679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01568
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